SLC6A4 gene 5-HTTLPR distribution in futsal and football players
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https://doi.org/10.5281/zenodo.10886110Keywords:
Football, Futsal, Genetics, SLC6A4Abstract
In this study, we investigated the distribution of the S and L alleles of the 5-HTTLPR promoter region of the SLC6A4 gene in male and female futsal and football players. A total of 48 athletes participated in the study, including 12 female football players, 12 female futsal players, 12 male football players and 12 male futsal players with an average age of 22.25 years, who have been active in sports for at least five years and who were selected voluntarily and randomly. When analysing the allele and genotype distribution of the athletes’ 5-HTTLPR polymorphisms, it was found that they had (56.2%) S, (43.8%) L alleles, 31.2% S/S, 50% L/S and 50% L/L genotypes. In the 5-HTTLPR/rs25531 polymorphism, significant results were found in the allele distribution between the branches (p<0.05), but no significant findings were found in genotype distribution (p>0.05). the “La” allele was found more frequently in football players, while the “S” allele was found more frequently in futsal players. For the 5-HTTLPR polymorphism, no significant finding was found in the allele and genotype distribution between the branches (p>0.05). The fact that the S allele and the S/S genotype were more common in the allele and genotype distribution of the athletes in the study than the L allele and the L/L genotype indicates that the futsal and football players participating in the study have a genetic predisposition to aggression. It was predicted that multi-gene research would be effective in defining phenotypes. It was suggested that sports genetics research should not be considered independent of epigenetic factors and that studies with larger sample groups should be conducted in this area.
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